P. Jarvinen et L. Hyvarinen, CONTRAST SENSITIVITY MEASUREMENT IN EVALUATIONS OF VISUAL SYMPTOMS CAUSED BY EXPOSURE TO TRIETHYLAMINE, Occupational and environmental medicine, 54(7), 1997, pp. 483-486
Objectives-To determine whether blurred vision caused by exposure to t
riethylamine (TEA) can be detected by the measurement of contrast sens
itivity. Methods-41 cold box core makers of three foundries and 82 con
trol workers were examined. A detailed ocular and medical history was
obtained from the subjects. The contrast sensitivity of the core maker
s was measured on Monday and Friday of the same week both before and i
mmediately after work and also on a third day, when air samples of TEA
were collected. Contrast sensitivity and visual acuity were measured
by optotype figures at full contrast, 2.5% contrast, and 0.6% contrast
. The changes in contrast sensitivity were used for the analysis. The
results of binocular vision and the results of the dominant eye were a
nalysed. Urine specimens for the analysis of TEA were collected on eve
ry occasion when contrast sensitivity was measured. Results-78% of the
core makers had had symptoms of blurred vision, and 31% had had troub
le driving or working. The breathing zone eight hour time weighted ave
rage TEA concentrations were 0.3-60 mg/m(3). The mean urinary TEA conc
entration after the shift was 35 mmol/mol creatinine. Continuous monit
oring showed high peaks of TEA leakage at a core making machine. Chang
es in binocular visual acuity did not differ between the exposed and u
nexposed workers. The contrast sensitivity of the core makers decrease
d significantly at both 2.5% and 0.6% contrast during the working day.
In the binocular measurements at 2.5% contrast, sensitivity decreased
in 49% of the core makers and 21% of the controls (P=0.002). Conclusi
ons-The blurred vision caused by exposure to TEA can be documented by
measuring contrast sensitivity. The mechanism by which TEA produces sy
mptoms remains an issue of further study.