Treatment of adult ALL according to protocols of the German Multicenter Study Group for Adult ALL (GMALL)

Authors
Gokbuget, N Hoelzer, D Arnold, R Bohme, A Bartram, CR Freund, M Ganser, A Kneba, M Langer, W Lipp, T Ludwig, WD Maschmeyer, G Rieder, H Thiel, E Weiss, A Messerer, D
Citation
N. Gokbuget et al., Treatment of adult ALL according to protocols of the German Multicenter Study Group for Adult ALL (GMALL), HEMAT ONCOL, 14(6), 2000, pp. 1307
Citations number
39
Categorie Soggetti
Hematology,"Cardiovascular & Hematology Research
Journal title
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
ISSN journal
08898588 → ACNP
Volume
14
Issue
6
Year of publication
2000
Database
ISI
SICI code
0889-8588(200012)14:6<1307:TOAAAT>2.0.ZU;2-7
Abstract
The German Multicenter Study Group for Adult Acute Lymphoblastic Leukemia ( GMALL) has conducted 5 consecutive trials with more than 3000 patients sinc e 1981. This article provides an overview on aims, treatment concepts, and results of these studies. It includes brief summaries on the development of prognostic models within the GMALL group and on approaches for prophylaxis of CNS relapse, and it summarizes specific treatment concepts for mature B -lineage acute lymphocytic leukemia.