Severity of group B streptococcal arthritis in selected strains of laboratory mice

Authors
Puliti, M Bistoni, F von Hunolstein, C Orefici, G Tissi, L
Citation
M. Puliti et al., Severity of group B streptococcal arthritis in selected strains of laboratory mice, INFEC IMMUN, 69(1), 2001, pp. 551-555
Citations number
17
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
69
Issue
1
Year of publication
2001
Pages
551 - 555
Database
ISI
SICI code
0019-9567(200101)69:1<551:SOGBSA>2.0.ZU;2-C
Abstract
The susceptibilities of C3H/HeN, BALB/c, and C57BL/6N mouse strains to grou p B streptococci (GBS) infection were evaluated. C3H/HeN mice developed sev ere polyarthitis; mild lesions and no lesions were observed in BALB/c and C 57BL/6N mice, respectively, a correlation between the severity of arthritis , the number of GBS in the joints, and local interleukin-6 and interleukin- 1 beta production was evident.