Five cases of Kallmann's syndrome are presented, out-patients with microtes
tes, hypogonadotropic hypogonadism and complete anosmia. The final diagnosi
s was made only when they were aged between 17 and 26 (mean 21 years), alth
ough they had been seen by several physicians before: 3 for cryptorchidism
and 3 for absence of spontaneous puberty; 2 had a positive family history,
and 4 of the 5 patients or their parents admitted that they were aware of t
he fact that their sense of smell was completely absent, but they did not m
ention it spontaneously.