Keratographic analysis of a family with keratoconus in identical twins

We screened family members of monozygotic twins with keratoconus to search for a corneal thinning disorder using clinical, videokeratographic, and pac hymetric analyses. The parents had bilateral astigmatism of a symmetric bow -tie pattern with normal videokeratographic;and pachymetric indices. The 8- year-old sister had slightly asymmetric astigmatism in both eyes with norma l pachymetry values. No family member was suspected of a corneal thinning d isorder. We discuss the mode of inheritance of keratoconus in this family. J Cataract Refract Surg 2000; 26:1830-1832 (C) 2000 ASCRS and ESCRS.