A non-smoking Asian woman with previously treated pulmonary tuberculos
is presented with a recent onset unproductive cough and cavitating mas
s lesion on her chest X-ray which rapidly developed into a large tuber
culous cavity after bronchoscopy. Acid-fast bacilli were isolated from
the cavity and she responded very rapidly to standard anti-tuberculou
s chemotherapy. This unusual condition must be considered in patients
who deteriorate after bronchoscopy.