NAUSEA AND VOMITING AFTER GYNECOLOGICAL L APAROSCOPY - PROPOFOL SUFENTANIL VERSUS THIOPENTONE/ISOFLURANE/SUFENTANIL/

There is a high incidence of postoperative nausea and vomiting after l aparoscopic surgery. We evaluated the effect of propfol/sufentanil ana esthesia in comparison to isoflurane/thiopental/sufentanil anaesthesia with regard to postoperative nausea, vomiting, recovery and shivering , Methods: Sixty ASA I and II patients scheduled for gynaecological la paroscopy were randomly assigned to two groups, Anaesthesia in Group o ne (n = 30) was induced with sufentanil 0,4 mu g.kg(-1), thiopental 4 mg.kg(-1) and atracurium 0,4 mg.kg(-1). Anaesthesia was maintained wit h isoflurane 1,2 +/- 0,3 MAC and repetitive doses of sufentanil and at racurium. Group two received propofol 1,5 to 2 mg.kg(-1) and an identi cal dose of sufentanil and atracurium as group one, For maintenance we gave propofol 6 to 10 mg.kg(-1).h(-1) and repetitive doses of sufenta nil and atracurium. N2O was avoided in both groups, For postoperative examination we used a scoring system, Results: In both groups 9 patien ts suffered from nausea, in group one 2 patients vomited, in group two 1 patient, Group two had a higher recovery score when arriving in the postanaesthetic care unit, After 30 min there was no further differen ce in recovery between the groups, For shivering no intergroup differe nces were found, Conclusion: A nitrous oxide free isoflurane/sufentani l lon flow anaesthesia for laparoscopies produces clinically comparabl e results to a propofol/sufentanil anaesthesia however at lower costs.