Important comorbidities recorded on outpatient claims in administrative dat
asets may be missed in analyses when only inpatient care is considered. Usi
ng the comorbid conditions identified by Charlson and colleagues, we develo
ped a comorbidity index that incorporates the diagnostic and procedure data
contained in Medicare physician (Part B) claims. In the national cohorts o
f elderly prostate (n = 28,868) and breast cancer (n = 14,943) patients ass
essed in this study, less than 10% of patients had comorbid conditions iden
tified when only Medicare hospital (Part A) claims were examined. By incorp
orating physician claims, the proportion of patients with comorbid conditio
ns increased to 25%. The new physician claims comorbidity index significant
ly contributes to models of 2-year noncancer mortality and treatment receiv
ed in both patient cohorts. We demonstrate the utility of a disease-specifi
c index using an alternative method of construction employing study-specifi
c weights. The physician claims index can be used in conjunction with a com
orbidity index derived from inpatient hospital claims, or employed as a sta
nd-alone measure. (C) 2000 Elsevier Science Inc. All rights reserved.