Left ventricular volumes, ejection fraction, and regional wall motion calculated with gated technetium-99m tetrofosmin SPECT in reperfused acute myocardial infarction at super-acute phase: Comparison with left ventriculography
M. Abe et al., Left ventricular volumes, ejection fraction, and regional wall motion calculated with gated technetium-99m tetrofosmin SPECT in reperfused acute myocardial infarction at super-acute phase: Comparison with left ventriculography, J NUCL CARD, 7(6), 2000, pp. 569-574
Background. Noninvasive assessment of acute myocardial infarction (AMT) req
uires information about both myocardial perfusion and left ventricular (LV)
function. The automated quantification of electrocardiographic-gated myoca
rdial scintigraphy with technetium-99m tetrofosmin (QGS) can provide this i
nformation.
Methods and Results, Coronary arteriography, QGS, and left ventriculography
(LVG) were performed in 229 patients with reperfused AMI within 2 days aft
er onset. All infarcted vascular territories (229 segments) were visualized
with scintigraphic perfusion images, The mean wall motion score (WMS) was
15.9 +/- 2.8 by means of QGS and 16.3 +/- 2.9 by means of LVG, The correlat
ion between WMS obtained by means of QGS and that obtained by means of LVG
was close (y = 0.913x + 1.016, r = 0.94, P <.001), but that obtained by mea
ns of QGS was significantly lower than that obtained by means of LVG (P <.0
001). Total agreement for the assessment of regional wall motion reached 75
% (kappa, 0.66). Although the LV values obtained by means of QGS and LVG co
rrelated well (end-diastolic volume, r = 0.67, P <.0001; end-systolic volum
e, r = 0.79, P <.0001; ejection fraction, r = 0.78, P <.0001), end-diastoli
c volume and ejection fraction tended to be underestimated with QGS.
Conclusion. QGS data were considered to be useful in detecting infarcted va
scular territory and LV function, even in AMI, within 2 days after onset.