Radioactive skin contamination with radionuclides in ionic forms after the
permeation across skin models was studied in vitro. Using animal skin model
s of 5-day-old rat and 9-day-old rat, either intact or stripped, it was fou
nd that besides the transepidermal also the transfolicular flux can be impo
rtant. Stratum corneum was found to be the principal permeation barrier in
all cases. The study of penetration - time profiles revealed that permeated
amounts were proportional to time in the case of Cs-137(+) and Co-60(2+),
but they showed a local maximum in the case of Pm-147(3+).