Sympathetic skin response (SSR) was performed before and 1 year after surgi
cal release of the median nerve in 20 subjects (mean age 52.8 years) with u
nilateral idiopathic carpal tunnel syndrome (CTS). SSR was evoked by stimul
ation of the ulnar nerve at the wrist contralateral to the side with CTS, r
ecording from the palm, third (M3) and fifth fingers, and from the third fi
nger contralateral to the side of CTS (M3c). Before surgery, anomalies of M
3 SSR were found in 8 hands (40%): M3 SSR was absent in 1 hand; and the M3c
/M3 SSR largest area ratio was abnormal in 7 hands, 3 of which also had abn
ormal mean differences between M3 and M3c SSR latencies. M3 SSRs were not s
ignificantly modified after surgery. The absence of postsurgical improvemen
t may be due to the poor reinnervation capacity of sympathetic fibers. (C)
2001 John Wiley & Sons, Inc.