It will be shown that the contribution of Arnold Pick (1851-1924) goes far
beyond the first description of the disorder associated with his name. His
view that the process of dementia should not be conceptualised as a diffuse
degradation of mental abilities but as a mosaic of circumscribed neuropsyc
hological deficits is as modern now as it was then and is a prerequisite fo
r the differential diagnosis of degenerative dementias during life.