The authors analyzed whether the pituitary gland enlarges in intracranial h
ypotension syndrome by studying 11 consecutive patients. Initial MRI scans
showed pituitary gland enlargement with a convex superior margin. Follow-up
MRI studies revealed that the size of the gland invariably diminished in a
ll patients. The authors hypothesize that pituitary gland enlargement in in
tracranial hypotension syndrome is due to hyperemia of dural and epidural v
enous sinuses.