Excitable calcium wave propagation in the presence of localized stores

Citation
Cs. Pencea et Hge. Hentschel, Excitable calcium wave propagation in the presence of localized stores, PHYS REV E, 62(6), 2000, pp. 8420-8426
Citations number
19
Categorie Soggetti
Physics
Journal title
PHYSICAL REVIEW E
ISSN journal
1063651X → ACNP
Volume
62
Issue
6
Year of publication
2000
Part
B
Pages
8420 - 8426
Database
ISI
SICI code
1063-651X(200012)62:6<8420:ECWPIT>2.0.ZU;2-P
Abstract
We study the propagation of calcium waves in the presence of a discrete dis tribution of calcium stores. Calcium-induced calcium release coupled to dif fusion can be used to produce a criterion for wave propagation across conne cted clusters of stores. The velocity of the resulting wave and its relatio nship to the frequency of the excitatory stimulus can then be described usi ng percolation theory. Simulations show a homogenous and a fractal regime a nd are in agreement with both experiments and theory.