Diterpenes from Laennecia sophiifolia

From the aerial parts of Laennecia sophiifolia (Kunth) G.L. Nesom, a neo-cl erodane and an acyclic furano diterpene were isolated, along with four know n compounds, 2 beta -hydroxyhardwickiic acid, hawtriwaic acid, apigenin, an d beta -sitosterol. Their structures were established as 12-epi-bacchotricu neatin A and (2E,6E)-9-(3-furyl)-6-methyl-2-(4-methylpent-3-enyl)-nona-2,6- dienoic acid, by analysis of spectral evidence. The absolute structure of 1 2-epi-bacchotricuneatin A was determined by a circular dichroism spectral c omparison with that of bacchotricuneatin A. (C) 2000 Elsevier Science Ltd. All rights reserved.