Anthrone and oxanthrone C,O-diglycosides from Picramnia teapensis

Two C,O-diglycosylated compounds, the anthrone picramnioside F, and the oxa nthrone mayoside C, were isolated from the stem bark of Picramnia teapensis , along with the previously reported anthraquinones, 1-O-beta -D- and 8-O-b eta -D-glucopyranosyl emodin. The compounds were separated by recycling-HPL C, and their structures were determined on the basis of spectroscopic analy sis. CD measurements were used to establish the absolute configuration of t he anthrone and oxanthrone. The antifungal activity of 1-O-beta -D- and 8-O --D-glucopyranosyl emodin against Leucoagaricus gongilophorus was shown to be similar to that of the lignan sesamin. (C) 2000 Elsevier Science Ltd. Al l rights reserved.