Fp. Dunne et al., Fetal and maternal outcomes in Indo-Asian compared to Caucasian women withdiabetes in pregnancy, QJM-MON J A, 93(12), 2000, pp. 813-818
Citations number
23
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS
Maternal and fetal complications are increased when pregnancy is complicate
d by diabetes, and this may be further influenced by racial and cultural di
fferences. We examined fetal and maternal outcomes in Indo-Asian and Caucas
ian women attending the same antenatal diabetes service to see if there wer
e any differences. Women with diabetes mellitus (type 1, type 2 and gestati
onally-acquired disease) complicating pregnancy, registered at the combined
diabetes/antenatal clinic of this University teaching hospital over the pe
riod 1990-1998 were included. Fetal outcomes examined were miscarriage <24
weeks, stillbirths, neonatal deaths up to 28 days of life, perinatal mortal
ity, congenital malformations and size for gestational age. Maternal outcom
es examined were rates of caesarean section and vaginal deliveries, and num
ber of pre-term deliveries <37 completed weeks of gestation. Outcomes for I
ndo-Asian and Caucasian women were similar, with a take-home baby rate of 9
6% and 92%, respectively. There was no perinatal mortality in Indo-Asian wo
men, who were more likely to have a vaginal delivery and less likely to hav
e a baby large for gestational age. Pregnancies complicated by type 2 diabe
tes in both groups pose the greatest threat to a successful pregnancy outco
me. Indo-Asian and Caucasian women attending the same antenatal diabetes se
rvice have comparable outcomes. Attendance for pre-pregnancy care needs to
be encouraged to combat the high early pregnancy loss and congenital malfor
mation rate identified, particularly in those with type 2 disease, irrespec
tive of ethnicity.