MRI is the most accurate noninvasive technique available for assessment of
normal articular cartilage and cartilage lesions. MRI cannot only provide m
orphologic information about the area of damage, but can also provide uniqu
e insight into the biochemical composition of the articular cartilage. New
image processing techniques such as three-dimensional mapping of cartilage
thickness will help to establish automated analysis of cartilage loss. Thes
es techniques are ideally suited for monitoring patients who undergo treatm
ent with new chondroregenerative drugs.