Introduction. - Thiamine deficiency can be determined by various clinical s
igns; some of these symptoms may be acute, and require an urgent diagnosis.
In countries such as ours with a high standard of living, this disorder is
more commonly observed in cases of severe alcoholism, and cases of diet-as
sociated thiamine deficiency are rare, and therefore not easily recognized.
The metabolic disorders resulting from vitamin B-1 deficiency are responsi
ble for the well-known central or peripheral neurological-symptoms, and als
o for the less common and often more acute cardiovascular reactions. Immedi
ate thiamine/vitamin B-1 supplementation is of major importance. The rapid
reversal of symptoms following this treatment is often considered as a diag
nostic index.
Exegesis, - In this study, an original case of diet-associated thiamine def
iciency has been reported with clinical symptoms including myocarditis and
subacute peripheral nerve involvement in a young adult. The disorder was th
e result of a thiamine deficiency in the diet, which was exclusively based
on milled rice.
Conclusion. - The present report is interesting both as regards its clinica
l aspects and its etiology, and it emphasizes the importance in the differe
ntial diagnosis of a given case of taking the possibility of diet-related t
hiamine deficiency into account, although this is an uncommon etiology in d
eveloped countries. (C) 2000 Editions scientifiques et medicales Elsevier S
AS.