PYRROLODIAZINES .4. STRUCTURE AND CHEMISTRY OF 3,4-DIHYDROPYRROLO[1,2-A]PYRAZINE

Authors
MINGUEZ JM CASTELLOTE I VAQUERO JJ NAVIO JLG ALVAREZBUILLA J CASTANO O ANDRES JL
Citation
Jm. Minguez et al., PYRROLODIAZINES .4. STRUCTURE AND CHEMISTRY OF 3,4-DIHYDROPYRROLO[1,2-A]PYRAZINE, Tetrahedron, 53(27), 1997, pp. 9341-9356
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
27
Year of publication
1997
Pages
9341 - 9356
Database
ISI
SICI code
0040-4020(1997)53:27<9341:P.SACO>2.0.ZU;2-V
Abstract
The structure of 3,4-dihydropyrrolo[1,2-a]pyrazine and its N-protonate d form is studied by ab initio calculations. Examples of the reactivit y of this poorly studied system are presented in which it is shown tha t the imino moiety does not react with dienes but does undergo inter- and intramolecular 1,3-dipolar cycloadditions by reaction of azomethin e ylides of this bicyclic system with suitable dipolarophiles. (C) 199 7 Elsevier Science Ltd.