A practical and highly efficient synthesis of alpha-(trimethylsilyl)-difluoroacetates

Authors
Amii, H Kobayashi, T Uneyama, K
Citation
H. Amii et al., A practical and highly efficient synthesis of alpha-(trimethylsilyl)-difluoroacetates, SYNTHESIS-S, (14), 2000, pp. 2001-2003
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
14
Year of publication
2000
Pages
2001 - 2003
Database
ISI
SICI code
0039-7881(200012):14<2001:APAHES>2.0.ZU;2-2
Abstract
An efficient method for the gram scale preparation of alpha-(trimethylsilyl )difluoroacetates is described. The key step involves Mg(0)-promoted select ive C-F bond cleavage of readily available trifluoroacetates.