Synthesis of tris(pyrazolyl)methanes of unprecedented complexity and functionality

Authors
Goodman, MS Bateman, MA
Citation
Ms. Goodman et Ma. Bateman, Synthesis of tris(pyrazolyl)methanes of unprecedented complexity and functionality, TETRAHEDR L, 42(1), 2001, pp. 5-7
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
1
Year of publication
2001
Pages
5 - 7
Database
ISI
SICI code
0040-4039(20010101)42:1<5:SOTOUC>2.0.ZU;2-T
Abstract
In this paper we show that simple tris(pyrazolyl)methane (Tpm) ligands can be equilibrated with substituted pyrazoles to form new 'mixed' tris(pyrazol yl)methanes. The product ratio depends on the nature of the starting tris(p yrazolyl)methane, the nature of the substituted pyrazole, and the relative amounts of these two reagents. The method has been used to easily synthesiz e several new asymmetric and functionalized Tpm ligands. (C) 2000 Elsevier Science Ltd. All rights reserved.