Toward the synthesis of the antibiotic tetrodecamycin

Authors
Paintner, FF Bauschke, G Kestel, M
Citation
Ff. Paintner et al., Toward the synthesis of the antibiotic tetrodecamycin, TETRAHEDR L, 41(51), 2000, pp. 9977-9980
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
51
Year of publication
2000
Pages
9977 - 9980
Database
ISI
SICI code
0040-4039(200012)41:51<9977:TTSOTA>2.0.ZU;2-U
Abstract
We report here a short approach to a tricyclic substructure of tetrodecamyc in exhibiting a unique ring skeleton utilising an acid catalysed ring closu re as the key step. In addition an efficient three-step synthesis of 5-alky lidene 4-methoxy-2(5H)-furanones starting from 4-methoxy-2(5H)-furanone is described. (C) 2000 Elsevier Science Ltd. All rights reserved.