A convenient synthesis of some 4-(alkylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones

Authors
Kahveci, B Ikizler, AA
Citation
B. Kahveci et Aa. Ikizler, A convenient synthesis of some 4-(alkylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones, TURK J CHEM, 24(4), 2000, pp. 343-351
Citations number
20
Categorie Soggetti
Chemistry
Journal title
TURKISH JOURNAL OF CHEMISTRY
ISSN journal
13000527 → ACNP
Volume
24
Issue
4
Year of publication
2000
Pages
343 - 351
Database
ISI
SICI code
1300-0527(2000)24:4<343:ACSOS4>2.0.ZU;2-V
Abstract
A series of 3-alkyl-4- (arylidenamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones, 6-10, was obtained from the reaction of the corresponding 3-alkyl-4-amino- 4,5-dihydro-1H- 1,2,4-triazol-5-ones, 1, with the appropriate aldehydes. 3- alkyl-4-(alkylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones of type 11-16 were synthesized from the selective reduction of compounds 5-10 with NaBH4 in d iglyme or DMSO medium as a general and convenient method.