Bilateral pulmonary edema after endoscopic sympathectomy in a patient withglucose-6-phosphate dehydrogenase deficiency

Transaxillary endoscopic sympathectomy of thoracic ganglia (T-2-T-3) has re cently gained wider acceptance as the treatment of choice for palmar hyperh idrosis. It requires one-lung ventilation to facilitate the surgery. One-lu ng ventilation, however, is not without complications, among which acute pu lmonary edema has been reported. In this case report, we present a patient with palmar hyperhidrosis complicated by glucose-6-phosphate dehydrogenase (G-6-PD) deficiency, who received bilateral endoscopic sympathectomy under alternate one-lung anesthesia, and developed acute pulmonary edema immediat ely after recruitment of the successive collapsed lung. The effects of hypo xemia, G-6-PD deficiency and sympathectomy might all add to the development of acute pulmonary edema secondary to reexpansion of each individual lung after alternate one-lung ventilation. The possibilities of the inferred cau ses are herein discussed.