p53 codon 72 polymorphism in cervical cancer patients and healthy women from Poland

Authors
Dybikowska, A Dettlaff, A Konopa, K Podhajska, A
Citation
A. Dybikowska et al., p53 codon 72 polymorphism in cervical cancer patients and healthy women from Poland, ACT BIOCH P, 47(4), 2000, pp. 1179-1182
Citations number
14
Categorie Soggetti
Biochemistry & Biophysics
Journal title
ACTA BIOCHIMICA POLONICA
ISSN journal
0001527X → ACNP
Volume
47
Issue
4
Year of publication
2000
Pages
1179 - 1182
Database
ISI
SICI code
0001-527X(2000)47:4<1179:PC7PIC>2.0.ZU;2-4
Abstract
A polymorphism at codon 72 of gene p53 results in the presence of either ar ginine or proline at this position. We investigated the distribution of p53 codon 72 polymorphism in cervical cancer patients and a control group of h ealthy women from Poland. Our results do not confirm the hypothesis that th e p53 codon polymorphism could play a role as a factor for squamous carcino ma of the cervix.