There is evidence that chronic pain disorders such as Myofascial Pain Syndr
ome (MPS), resulting from repeated biomechanical stress caused by ergonomic
hazards. e.g. trauma and overuse of the muscles, often occur in agricultur
al workers. Hypothetically, the neuropathic character of MPS makes the dise
ase unresponsive to the typical analgesics. Accordingly, in this study thre
e trials of treatment in patients with MPS were performed and compared. The
first trial (1) was based on rehabilitation. while the second (II) was bas
ed on treatment with sertraline, an antidepressive. serotoninergic drug. Fo
r third trial (III), rehabilitation plus the above-mentioned administration
of sertraline, were applied. Altogether. 49 patients were recruited to the
trials. Control group consisted of 23 persons. Response to the treatment w
as assessed according to the criteria of neuropsychoiogical tests MADRS and
BDI. The MPS syndrome was found to be relatively common in Polish farmers
and formed 12.7% of all chronic pain syndromes diagnosed in the Institute o
f Agricultural Medicine during 18 months. All the patients with MPS showed
mood disorders in the baseline assessment by the neuropsychological tests.
Patients from groups I. II. and III declared improvement after two, months
of the treatment (77%, 80% and 93% respectively). In the neuropsychological
tests, only patients treated with rehabilitation and sertraline (group III
) showed statistically significant improvement in comparison with baseline
assessment both after one month and after two months of the observation. Th
us. rehabilitation and serotoninergic system modification might be a good s
olution in the management of MPS.