Catalytic antibodies (abzymes) induced by stable transition-state analogs

Authors
Nevinsky, GA Semenov, DV Buneva, VN
Citation
Ga. Nevinsky et al., Catalytic antibodies (abzymes) induced by stable transition-state analogs, BIOCHEM-MOS, 65(11), 2000, pp. 1233-1244
Citations number
85
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOCHEMISTRY-MOSCOW
ISSN journal
00062979 → ACNP
Volume
65
Issue
11
Year of publication
2000
Pages
1233 - 1244
Database
ISI
SICI code
0006-2979(200011)65:11<1233:CA(IBS>2.0.ZU;2-J
Abstract
This review deals with recent advances in the generation of catalytic antib odies by the immunization of animals with stable transition-state analogs. Characteristic features in the functioning of such abzymes are considered i n comparison with traditional enzymes.