Natural catalytic antibodies (abzymes) in normalcy and pathology

Authors
Nevinsky, GA Kanyshkova, TG Buneva, VN
Citation
Ga. Nevinsky et al., Natural catalytic antibodies (abzymes) in normalcy and pathology, BIOCHEM-MOS, 65(11), 2000, pp. 1245-1255
Citations number
81
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOCHEMISTRY-MOSCOW
ISSN journal
00062979 → ACNP
Volume
65
Issue
11
Year of publication
2000
Pages
1245 - 1255
Database
ISI
SICI code
0006-2979(200011)65:11<1245:NCA(IN>2.0.ZU;2-E
Abstract
This review summarizes literature data on natural abzymes. Peculiar feature s of their functioning and substrate specificity are considered in comparis on with traditional enzymes. Working hypotheses on the possible biological roles of natural abzymes in autoimmune processes and diseases accompanied b y disorders of immune status are analyzed.