Synthesis of a hybrid fullerene-trimethoxyindole-oligonucleotide conjugate

Citation
M. Bergamin et al., Synthesis of a hybrid fullerene-trimethoxyindole-oligonucleotide conjugate, CHEM COMMUN, (01), 2001, pp. 17-18
Citations number
14
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
01
Year of publication
2001
Pages
17 - 18
Database
ISI
SICI code
1359-7345(2001):01<17:SOAHFC>2.0.ZU;2-9
Abstract
The synthesis of novel functionalized fullerene derivatives is reported: a DNA minor groove binder such as trimethoxy-indole-2-carboxylate (TMI) and a n oligonucleotide chain have been covalently linked to C-60 with the aim of duplicating DNA interactions for increasing sequence selectivity.