The biosynthesis of bisorbicillinoids: evidence for a biosynthetic route from bisorbicillinol to bisorbibutenolide and bisorbicillinolide

Authors
Abe, N Yamamoto, K Arakawa, T Hirota, A
Citation
N. Abe et al., The biosynthesis of bisorbicillinoids: evidence for a biosynthetic route from bisorbicillinol to bisorbibutenolide and bisorbicillinolide, CHEM COMMUN, (01), 2001, pp. 23-24
Citations number
14
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
01
Year of publication
2001
Pages
23 - 24
Database
ISI
SICI code
1359-7345(2001):01<23:TBOBEF>2.0.ZU;2-7
Abstract
Biosynthetic incorporation of labelled sodium acetates into bisorbicillinol in Trichoderma sp. USF-2690 suggests that bisorbicillinol is derived from 12 acetate units. Successful bioconversion of the labelled bisorbicillinols to bisorbibutenolides (bislongiquinolides) and bisorbicillinolides using t he washed mycelium of the strain suggests that there are biosynthetic route s from bisorbicillinol to bisorbibutenolide and from bisorbicillinol to bis orbicillinolide.