Dynamic kinetic resolution of tert-butyl 4-methyl-3,5-dioxohexanoate through enzymatic reduction

Authors
Ji, AG Wolberg, M Hummel, W Wandrey, C Muller, M
Citation
Ag. Ji et al., Dynamic kinetic resolution of tert-butyl 4-methyl-3,5-dioxohexanoate through enzymatic reduction, CHEM COMMUN, (01), 2001, pp. 57-58
Citations number
22
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
01
Year of publication
2001
Pages
57 - 58
Database
ISI
SICI code
1359-7345(2001):01<57:DKROT4>2.0.ZU;2-X
Abstract
An entirely new method for the dynamic kinetic resolution of a racemic, 2-m ethyl substituted, unsymmetrical 1,3-diketone via enzymatic reduction to gi ve an enantiomerically pure compound is introduced.