Enantioselective hydrolysis of amino acid esters by apomyoglobin: perfect kinetic resolution of a phenylalanine derivative

Authors
Tomisaka, K Ishida, Y Konishi, K Aida, T
Citation
K. Tomisaka et al., Enantioselective hydrolysis of amino acid esters by apomyoglobin: perfect kinetic resolution of a phenylalanine derivative, CHEM COMMUN, (01), 2001, pp. 133-134
Citations number
21
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
01
Year of publication
2001
Pages
133 - 134
Database
ISI
SICI code
1359-7345(2001):01<133:EHOAAE>2.0.ZU;2-U
Abstract
Apoprotein of horse-heart myoglobin promoted enantioselective hydrolysis of 4-nitrophenyl esters of amino acids, which allowed nearly perfect kinetic resolution of racemic N-Boc-phenylalanine ester (Boc-Phe-ONp).