trans-3,4-Dihydroxy-1-selenolane oxide: A new reagent for rapid and quantitative formation of disulfide bonds in polypeptides

Citation
M. Iwaoka et S. Tomoda, trans-3,4-Dihydroxy-1-selenolane oxide: A new reagent for rapid and quantitative formation of disulfide bonds in polypeptides, CHEM LETT, (12), 2000, pp. 1400-1401
Citations number
16
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY LETTERS
ISSN journal
03667022 → ACNP
Issue
12
Year of publication
2000
Pages
1400 - 1401
Database
ISI
SICI code
0366-7022(200012):12<1400:TOANRF>2.0.ZU;2-M
Abstract
The title compound was found to be a powerful quantitative reagent for the formation of the disulfide bonds in polypeptides in a wide range of pH in t he oxidative regeneration experiments of bovine pancreatic ribonuclease A ( RNase A).