Controlled detachment of immobilized liposomes on polymer gel support

Immobilization of small liposomes on polymer gel beads and controlled detac hment of the liposomes from the support was described. Liposomes were immob ilized on the gel with hydrophobic anchors that contained disulfide linkage . The liposomes were then detached by reductive cleavage of the linkage wit h dithiothreitol. The major part of the fluorescein-conjugated dextran enca psulated in the liposomes was retained throughout the immobilization-detach ment process.