Synthesis and biological activity of yuccagenin bisrhamnoside

Citation
Ns. Pal'Yants et al., Synthesis and biological activity of yuccagenin bisrhamnoside, CHEM NAT CO, 36(3), 2000, pp. 299-301
Citations number
6
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
CHEMISTRY OF NATURAL COMPOUNDS
ISSN journal
00093130 → ACNP
Volume
36
Issue
3
Year of publication
2000
Pages
299 - 301
Database
ISI
SICI code
0009-3130(200005/06)36:3<299:SABAOY>2.0.ZU;2-#
Abstract
The two hydroxyls of yuccagenin can be glycosylated by Koenigs-Knorr conden sation with acetobromorhamnose in dichloroethane in the presence of mercuri c cyanide. The bisrhamnoside of yuccagenin markedly lowers the cholesterol and triglyceride content in blood serum of healthy animals and animals with experimental hyperlipidemia.