Chelating agents

Citation
T. Bergan et al., Chelating agents, CHEMOTHERA, 47(1), 2001, pp. 10-14
Citations number
14
Categorie Soggetti
Pharmacology,"Pharmacology & Toxicology
Journal title
CHEMOTHERAPY
ISSN journal
00093157 → ACNP
Volume
47
Issue
1
Year of publication
2001
Pages
10 - 14
Database
ISI
SICI code
0009-3157(200101/02)47:1<10:CA>2.0.ZU;2-X
Abstract
The antibacterial activity of metal ions, metal chelates, and molecules wit h chelating ability for polyvalent cations have been evaluated. The chelato r N,N'-ethylenebis[2-(2-hydroxyphenyl)-glycine] (EHPG) exerted moderate-to- good activity against isolates of pathogenic bacteria and fungi, Other chel ating agents such as ethylenediamine-tetraacetic acid (EDTA) and diethylene -triamine-pentaacetic acid (DIPA) revealed weak-to-moderate activity. Metal chelation of ligands reduced the activity of EDTA and DTPA, Copyright (C) 2001 S. Karger AG, Basel.