Chelating agents

The antibacterial activity of metal ions, metal chelates, and molecules wit h chelating ability for polyvalent cations have been evaluated. The chelato r N,N'-ethylenebis[2-(2-hydroxyphenyl)-glycine] (EHPG) exerted moderate-to- good activity against isolates of pathogenic bacteria and fungi, Other chel ating agents such as ethylenediamine-tetraacetic acid (EDTA) and diethylene -triamine-pentaacetic acid (DIPA) revealed weak-to-moderate activity. Metal chelation of ligands reduced the activity of EDTA and DTPA, Copyright (C) 2001 S. Karger AG, Basel.