Objective: To determine whether homoeopathic Arnica can reduce postoperativ
e haematomas in venous surgery. Design: Randomized, prospective, multicentr
ic, double-blind placebo-controlled trial. Participants: 130 consecutive pa
tients undergoing saphenous stripping (204 legs), hospitalized in a clinic,
interventions: A homoeopathic medicine (Arnica CH5) and an indistinguishab
le placebo, administered sublingually by a nurse the night before and immed
iately after the operation. Outcome Measures: Clinical evaluation of haemat
omas 6 days postoperatively. Results: Groups were well matched (sex, age, h
istory of bleeding or thrombosis, drug intake, previous intake of homoeopat
hic drugs, type of operation and anaethesia, operator). One drop-out has be
en replaced. No statistically significant difference in postoperative haema
tomas was found between the Arnica and placebo groups (p = 0.342), Subanaly
sis of all other items did not reveal any statistical difference either. Co
nclusions: In this study, with this dosage, we did not observe any preventi
ve effect of homoeopathic Arnica CH5 on poststripping haematomas. Copyright
(C) 2000 S. Karger AG, Basel.