A case of obesity, diabetes and hypertension treated with very low caloriediet (VLCD) followed by successful pregnancy with intrauterine insemination (IUI)

The patient was a 32-year-old obese woman with a history of type 2 diabetes and hypertension for 6 years. Although she was treated with antihypertensi ve agents and intensive insulin therapy, her hyperglycemia was difficult to control. She wanted to have a baby but pregnancy was not recommended becau se her diabetes was under poor control and the use of antihypertensive medi cation. To achieve good control of obesity, diabetes and hypertension, she was admitted to our clinical department for weight reduction using very low calorie diet (VLCD). During VLCD she had a 19.8 kg reduction in body weigh t and her blood glucose and blood pressure were in good control without the use of drugs. Five months later, she became pregnant after the fourth tria l of intrauterine insemination (IUI) and gave birth to a female baby under insulin therapy. This is the first report that showed the usefulness of VLC D for prepregnant control of glucose metabolism and blood pressure in an ob ese hypertensive patient with type 2 diabetes mellitus.