No recent update is available on long-term results of the various types of
treatment of obstructive sleep apnea (OSA) which can help the physician in
evaluating the individually tailored treatment for patients with OSA in the
long term. We arbitrarily defined "long-term" results as those after at le
ast 3 years and reviewed the literature from the past 25 years for reports
on conservative, apparative, and surgical therapy of OSA in children and ad
ults. Another inclusion criterion was that the diagnosis was also confirmed
by polysomnography before treatment and at follow-up. Only relatively few
long-term studies meeting the criteria of 'evidence based medicine' were fo
und, comparing the findings of these was difficult or impossible due to var
ying criteria for success. Long-term data were available about the effect o
f weight reduction, nasal ventilation therapy, oral devices, tonsillectomy,
uvulopalatopharyngoplasty, maxillomandibular advancement osteotomies, and
tracheotomy. After approx. 25 years many treatment modalities in sleep medi
cine are still experimental concerning the long-term use for the individual
. In particular, randomized controlled trials in surgery are lacking. Late
results show that at least 50% of patients with OSA can be treated effectiv
ely by one or a combination of treatments. Nasal continuous positive airway
pressure, tracheotomy, maxillomandibular advancement osteotomy, and tonsil
lectomy are the most effective treatments of OSA.