Mitral regurgitation (MR) is a frequent complication of end-stage heart fai
lure. Historically, these patients were either managed medically or with mi
tral valve replacement, both associated with poor outcomes. Mitral valve re
pair via an 'undersized' annuloplasty repair is safe arid effectively corre
cts MR in heart-failure patients. All of the observed changes contribute to
reverse remodeling and restoration of the normal left-ventricular geometri
c relationship. Mitral valve repair offers a new strategy for patients with
MR and end-stage heart failure. (C) European Society of Cardiology. AU rig
hts reserved.