The influence of fluoride ions on the viability, reduction of NBT, cytolysis, degranulation, and phagocytosis of human and rabbit neutrophils

Authors
Bober, J Kucharska, E Zawierta, J Machoy, Z Chlubek, D Ciechanowski, K
Citation
J. Bober et al., The influence of fluoride ions on the viability, reduction of NBT, cytolysis, degranulation, and phagocytosis of human and rabbit neutrophils, FLUORIDE, 33(3), 2000, pp. 108-114
Citations number
19
Categorie Soggetti
Biology
Journal title
FLUORIDE
ISSN journal
00154725 → ACNP
Volume
33
Issue
3
Year of publication
2000
Pages
108 - 114
Database
ISI
SICI code
0015-4725(200008)33:3<108:TIOFIO>2.0.ZU;2-N
Abstract
The influence of fluoride ion at concentrations of 10, 20, and 30 mmol/L on various properties of human and rabbit granulocytes was investigated. We f ound that fluoride ion inhibited phagocytes functions of rabbit granulocyte s, It also decreased the viability of rabbit polymorphonuclear leukocytes ( PMN) which was connected with increased degranulation. Fluoride ion activat ed mainly the oxygen-dependent bactericidal system in human neutrophils and the oxygen-independent one in rabbit neutrophils.