Synthesis and characterization of 2-alkylcarbamato-1,2,3,4-tetrahydro-1,3,2-benzodiazaphosphorine 2-oxides

Authors
Rao, LN Reddy, CD Raju, CN
Citation
Ln. Rao et al., Synthesis and characterization of 2-alkylcarbamato-1,2,3,4-tetrahydro-1,3,2-benzodiazaphosphorine 2-oxides, HETEROCYC C, 6(5), 2000, pp. 431-436
Citations number
10
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLIC COMMUNICATIONS
ISSN journal
07930283 → ACNP
Volume
6
Issue
5
Year of publication
2000
Pages
431 - 436
Database
ISI
SICI code
0793-0283(2000)6:5<431:SACO2>2.0.ZU;2-0
Abstract
Novel 2-alkylcarbamato-1,2,3,4-tetrahydro-1,3,2-benzodiazaphosphorine 2-oxi des (5a-h) have been synthesized from reaction of equimolar quantities of 2 -aminobenzylamine 2 with various dichlorophosphinyl carbamates 4 in dry tol uene in the presence of triethylamine at 40-45 degreesC. The title compound s (5a-h) at reflux temperature gave only 2-amino-1,2,3,4-tetrahydro-1,3,2-b enzodiazaphosphorine 2-oxide 6. The structures are characterized by IR. H-1 ,C-13,P-31 NMR and mass spectral studies.