A review deals with structure, synthesis, and reactivity of compounds
containing pentamethine systems (i.e. pentamethinium salts, aminopenta
dienals, glutaconic aldehydes, and cyanine dyes). Their syntheses of t
hese compounds via ring opening of the heterocycles, by building the s
keleton, or by addition reactions are described, as well as their reac
tivity to nucleophilic and electrophilic reagents, including ring-clos
ure reactions.