Effect of ring size on coordination properties of trans-1,2-cycloalkanediamine ligands: Synthesis of dinuclear platinum(II) complexes as potential DNA cross-linkers

Authors
Ongeri, S Aitken, DJ Husson, HP Kozelka, J Viossat, B
Citation
S. Ongeri et al., Effect of ring size on coordination properties of trans-1,2-cycloalkanediamine ligands: Synthesis of dinuclear platinum(II) complexes as potential DNA cross-linkers, INORG CHEM, 39(26), 2000, pp. 6131
Citations number
13
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
INORGANIC CHEMISTRY
ISSN journal
00201669 → ACNP
Volume
39
Issue
26
Year of publication
2000
Database
ISI
SICI code
0020-1669(200012)39:26<6131:EORSOC>2.0.ZU;2-P
Abstract
The propensity of trans-1,2-cycloalkanediamines (C-3-C-6) to form rigid din uclear complexes with platinum(II) was tested by reacting these ligands wit h K[PtCl3(dmso)]. Whereas trans-1,2-cyclopropanediamine and trans-1,2-cyclo butanediamine yielded dinuclear complexes in which the cycloalkane skeleton confines the platinum centers to a distance of ca. 6 Angstrom, trans-1,2-c ycropentanediamine and trans-1,2-cycrohexanediamine formed the chelates [Pt Cl(cycloalkanediamine)(dmso)](+), which precipitated with [PtCl3(dmso)](-) as counterion.