Treatment of lung cancer is often performed with cone-down oblique beams to
spare spinal cord and normal structures. However, there is no optimum tech
nique to determine oblique beam angles when a CT simulation is not availabl
e. Impact of oblique beam angle was investigated in this study. Fifteen pat
ients with centrally located lung tumors were immobilized and scanned using
a CT simulator, The target volumes, left and right lungs, and spinal cord
were delineated on each slice. Patients were simulated starting with anteri
or-posterior treatment beams and subsequently an oblique opposed pair beam
from 0 degrees up to 60 degrees at an interval of 5 degrees to optimize the
projection of target-to-cord distance and minimize the lung volume in the
treatment fields. Analysis was performed with a dose volume histogram (DVH)
in each beam orientation. The distance between the target volume and spina
l cord was linearly related to the angle of the beam. A larger angle facili
tated further sparing of the spinal cord; however, progressively more lung
volume was exposed. The 50% DVH data for lung volume was used as an indicat
or of lung volume, Although, the minimum lung volume was irradiated with an
angle of 30 degrees, the additional lung treated increased by only 8 +/- 7
% of the total lung volume for 30-60 degrees beam angles and cord distance
increased by 18.5 mm, A 30 degrees oblique parallel-opposed beam for the co
ne-down treatment of lung provided minimum lung volume in the irradiated fi
eld; however, the spinal cord distance increased Linearly with beam angle.
A CT simulator is ideally suited for simulation of lung cancer to maximize
the clearance from the spinal cord and minimize the additional lung volume
irradiated. Int. J. Cancer (Radiat. Oncol. Invest;) 90, 359-365 (2000). (C)
2000 Wiley-Liss, Inc.