This article provides (1) a comprehensive coverage of the literature on des
igns for estimating variance components, and (2) a review of recent applica
tions of such designs in genetics, statistical process control, and quality
improvement. In addition, recent methods of estimation of variance compone
nts and model forms, other than the linear, are discussed. The latter devel
opments have a direct effect on the choice of design. Some suggested ideas
for future research directions are also given.