PULVINATAL, A NOVEL BIOACTIVE METABOLITE FROM THE BASIDIOMYCETE NIDULARIA-PULVINATA (SCHW.) FR

Authors
BECKER U ERKEL G KOCKSCH G ANKE T STERNER O
Citation
U. Becker et al., PULVINATAL, A NOVEL BIOACTIVE METABOLITE FROM THE BASIDIOMYCETE NIDULARIA-PULVINATA (SCHW.) FR, Zeitschrift fur Naturforschung. C, A journal of biosciences, 52(5-6), 1997, pp. 313-318
Citations number
14
Categorie Soggetti
Biology
Journal title
Zeitschrift fur Naturforschung. C, A journal of biosciences → ACNP
ISSN journal
09395075
Volume
52
Issue
5-6
Year of publication
1997
Pages
313 - 318
Database
ISI
SICI code
0939-5075(1997)52:5-6<313:PANBMF>2.0.ZU;2-U
Abstract
Pulvinatal (1) was isolated from fermentations of Nidularia pulvinata as an inducer of differentiation of HL-60 promyelocytic leukemia cells . Its structure was elucidated by spectroscopic methods. In addition, N. pulvinata was found to produce 2,4,5-trihydroxy-6-methylbenzenecarb aldehyde (2) and orsellinic acid (3). Pulvinatal exhibits weak antifun gal and only marginal cytotoxic activities.