M. Bockmann et al., BACTERIAL CONSTITUENTS .70. BIOGENESIS OF THE PYOVERDIN CHROMOPHORE, Zeitschrift fur Naturforschung. C, A journal of biosciences, 52(5-6), 1997, pp. 319-324
After growing Pseudomonas aeruginosa in the presence of 2,4-[4-N-15]-d
iaminobutyric acid (Dab) its incorporation into the quinoline chromoph
ore of the pyoverdin produced by this bacterium could be shown by mass
and NMR-spectroscopic techniques. In combination with earlier results
it can thus be stated that the precursor of the chromophore is a cond
ensation product of L-Dab and D-Phe or D-Tyr. A synthesis for [4-N-15]
-Dab is described.