MAINTENANCE PHARMACOLOGICAL IMMUNOSUPPRESSIVE STRATEGIES IN RENAL-TRANSPLANTATION

Authors
VELLA JP SAYEGH MH
Citation
Jp. Vella et Mh. Sayegh, MAINTENANCE PHARMACOLOGICAL IMMUNOSUPPRESSIVE STRATEGIES IN RENAL-TRANSPLANTATION, Postgraduate medical journal, 73(861), 1997, pp. 386-390
Citations number
32
Categorie Soggetti
Medicine, General & Internal
Journal title
Postgraduate medical journal → ACNP
ISSN journal
00325473
Volume
73
Issue
861
Year of publication
1997
Pages
386 - 390
Database
ISI
SICI code
0032-5473(1997)73:861<386:MPISIR>2.0.ZU;2-H
Abstract
Current maintenance immunosuppressive regimens for transplantation are based on three classes of drugs: corticosteroids, immunophilin-bindin g agents (eg, cyclosporin and tacrolimus), and antimetabolites (eg, az athioprine and mycophenolate). Drugs from the various classes inhibit the immune system at different points and are thus synergistic when us ed in combination.